Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer

Abstract Purpose Specific gene fusions and their fusion products (chimeric RNA and protein) have served as ideal diagnostic markers and therapeutic targets for cancer. However, few systematic studies for chimeric RNAs have been conducted in neuroendocrine prostate cancer (NEPC). In this study, we ex...

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Bibliographic Details
Main Authors: Qiong Wang, Junxiu Chen, Sandeep Singh, Zhongqiu Xie, Fujun Qin, Xinrui Shi, Robert Cornelison, Hui Li, Hai Huang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-022-00893-5