Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

Objective: Chronic inflammatory response plays a prominent role in obesity-related nonalcoholic fatty liver disease (NAFLD). However, the intrahepatic triggering mechanism of inflammation remains obscure. This study aimed to elucidate the role of serum amyloid A1 (SAA1), an acute-phase response prot...

Full description

Bibliographic Details
Main Authors: Bin Jiang, Dongdong Wang, Yunfu Hu, Wenxuan Li, Fengjiang Liu, Xudong Zhu, Xiaoyu Li, Hanwen Zhang, Hui Bai, Qing Yang, Xiuna Yang, Jingjing Ben, Qi Chen
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Molecular Metabolism
Subjects:
Hepatic steatosis
Non-alcoholic fatty liver disease
NF-κB signaling pathway
Obesity
Serum amyloid A1
Toll-like receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782200031X

Internet

http://www.sciencedirect.com/science/article/pii/S221287782200031X

Similar Items