Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

Objective: Chronic inflammatory response plays a prominent role in obesity-related nonalcoholic fatty liver disease (NAFLD). However, the intrahepatic triggering mechanism of inflammation remains obscure. This study aimed to elucidate the role of serum amyloid A1 (SAA1), an acute-phase response prot...

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Bibliographic Details
Main Authors:	Bin Jiang, Dongdong Wang, Yunfu Hu, Wenxuan Li, Fengjiang Liu, Xudong Zhu, Xiaoyu Li, Hanwen Zhang, Hui Bai, Qing Yang, Xiuna Yang, Jingjing Ben, Qi Chen
Format:	Article
Language:	English
Published:	Elsevier 2022-05-01
Series:	Molecular Metabolism
Subjects:	Hepatic steatosis Non-alcoholic fatty liver disease NF-κB signaling pathway Obesity Serum amyloid A1 Toll-like receptor
Online Access:	http://www.sciencedirect.com/science/article/pii/S221287782200031X

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