Jupiter microtubule‐associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers

Jupiter microtubule‐associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers

Abstract Preoperative use of metformin in obese women with endometrioid endometrial cancer (EEC) reduces tumor proliferation and inhibits the mammalian target of rapamycin pathway, though is only effective in select cases. This study sought to identify a predictive and/or pharmacodynamic proteomic s...

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Bibliographic Details
Main Authors: Nicholas W. Bateman, Pang‐Ning Teng, Erica Hope, Brian L. Hood, Julie Oliver, Wei Ao, Ming Zhou, Guisong Wang, Domenic Tommarello, Katlin Wilson, Tracy Litzy, Kelly A. Conrads, Chad A. Hamilton, Kathleen M. Darcy, Yovanni Casablanca, George Larry Maxwell, Victoria Bae‐Jump, Thomas P. Conrads
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Cancer Medicine
Subjects:
endometrial cancer
hematological and neurological expressed 1
HN1
JPT1
Jupiter microtubule-associated homolog 1
metformin
Online Access:https://doi.org/10.1002/cam4.2729

Internet

https://doi.org/10.1002/cam4.2729

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