New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice

Objective(s): The study was aimed at synthesis of the new derivatives of the pyrazolone nucleus, and their spectroscopic and pharmacological analysis and evaluation. Materials and Methods: Three series of compounds, with 2-picolinic acid (I a-d), 3-picolinic acid (II a-d), and 4-picolinic acid (III...

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Bibliographic Details
Main Authors: Madiha Kanwal, Sadia Sarwar, Humaira Nadeem, Athar Ata, Fawad Shah, Sumra Malik, Saima Maqsood, Ghulam Miana
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-12-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_21186_e7a6dcef8ca32b3d9c313bb0c12ec2bc.pdf