Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

Objective: We have previously shown the existence of a muscle–pancreas intercommunication axis in which CX3CL1 (fractalkine), a CX3C chemokine produced by skeletal muscle cells, could be implicated. It has recently been shown that the fractalkine system modulates murine β-cell function. However, the...

Full description

Bibliographic Details
Main Authors: Sabine Rutti, Caroline Arous, Domitille Schvartz, Katharina Timper, Jean-Charles Sanchez, Emmanouil Dermitzakis, Marc Y. Donath, Philippe A. Halban, Karim Bouzakri
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Molecular Metabolism
Subjects:
Islets
Insulin secretion
Myokines
Survival
Insulin signaling pathway
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877814001331

Internet

http://www.sciencedirect.com/science/article/pii/S2212877814001331

Similar Items