eQTL mapping in fetal-like pancreatic progenitor cells reveals early developmental insights into diabetes risk

eQTL mapping in fetal-like pancreatic progenitor cells reveals early developmental insights into diabetes risk

Abstract The impact of genetic regulatory variation active in early pancreatic development on adult pancreatic disease and traits is not well understood. Here, we generate a panel of 107 fetal-like iPSC-derived pancreatic progenitor cells (iPSC-PPCs) from whole genome-sequenced individuals and ident...

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Bibliographic Details
Main Authors: Jennifer P. Nguyen, Timothy D. Arthur, Kyohei Fujita, Bianca M. Salgado, Margaret K. R. Donovan, iPSCORE Consortium, Hiroko Matsui, Ji Hyun Kim, Agnieszka D’Antonio-Chronowska, Matteo D’Antonio, Kelly A. Frazer
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42560-4

Internet

https://doi.org/10.1038/s41467-023-42560-4

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