Multi-target withaferin-A analogues as promising anti-kinetoplastid agents through the programmed cell death

Multi-target withaferin-A analogues as promising anti-kinetoplastid agents through the programmed cell death

Leishmaniasis and Chagas disease, two of the most prevalent neglected tropical diseases, are a world health problem. The harsh reality of these infective diseases is the absence of effective and safe therapies. In this framework, natural products play an important role in overcoming the current need...

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Bibliographic Details
Main Authors: Desirée San Nicolás-Hernández, Eduardo Hernández-Álvarez, Carlos J. Bethencourt-Estrella, Atteneri López-Arencibia, Ines Sifaoui, Isabel L. Bazzocchi, Jacob Lorenzo-Morales, Ignacio A. Jiménez, José E. Piñero
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Withaferin A analogues
Leishmaniasis
Chagas disease
Chemotherapy
Apoptosis-like
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223006698

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http://www.sciencedirect.com/science/article/pii/S0753332223006698

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