Impact of Synthesized Indoloquinoline Analog to Isolates from <i>Cryptolepis sanguinolenta</i> on Tumor Growth Inhibition and Hepatotoxicity in Ehrlich Solid Tumor-Bearing Female Mice

Impact of Synthesized Indoloquinoline Analog to Isolates from <i>Cryptolepis sanguinolenta</i> on Tumor Growth Inhibition and Hepatotoxicity in Ehrlich Solid Tumor-Bearing Female Mice

The study evaluated the antitumor efficacy of APAN, “synthesized indoloquinoline analog derived from the parent neocryptolepine isolated from the roots of <i>Cryptolepis sanguinolenta</i>”, versus the chemotherapeutic drug etoposide (ETO) in Ehrlich solid tumor (EST)-bearing female mice...

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Bibliographic Details
Main Authors: Amany E. Nofal, Elshaymaa I. Elmongy, Engy Abo Hassan, Ehab Tousson, Abdullah A. S. Ahmed, Ibrahim El Tantawy El Sayed, Reem Binsuwaidan, Manar Sakr
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
CD68
etoposide
APAN
survivin
topoisomerase II
TNF-α
Online Access:https://www.mdpi.com/2073-4409/12/7/1024

Internet

https://www.mdpi.com/2073-4409/12/7/1024

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