Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue.

Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue.

Memory impairment has been associated with chronic Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. In degenerative diseases, memory loss has been associated with increased oxidative stress, revealed as enhanced lipid peroxidation, in the cerebral...

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Main Authors: Glaucia Vilar-Pereira, Leda Castaño Barrios, Andrea Alice da Silva, Angelica Martins Batista, Isabela Resende Pereira, Otacílio Cruz Moreira, Constança Britto, Hílton Antônio Mata Dos Santos, Joseli Lannes-Vieira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244710

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https://doi.org/10.1371/journal.pone.0244710

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