Synthesis and Cytotoxicity Evaluation of Novel Coumarin–Palladium(II) Complexes against Human Cancer Cell Lines

Synthesis and Cytotoxicity Evaluation of Novel Coumarin–Palladium(II) Complexes against Human Cancer Cell Lines

Two newly synthesized coumarin–palladium(II) complexes (C1 and C2) were characterized using elemental analysis, spectroscopy (IR and <sup>1</sup>H-<sup>13</sup>C NMR), and DFT methods at the B3LYP-D3BJ/6-311+G(d,p) level of theory. The in vitro and in silico cytotoxicity of c...

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Bibliographic Details
Main Authors: Edina H. Avdović, Marko Antonijević, Dušica Simijonović, Sunčica Roca, Dražen Vikić Topić, Nađa Grozdanić, Tatjana Stanojković, Ivana Radojević, Radiša Vojinović, Zoran Marković
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
palladium(II) complexes
cytotoxicity
in silico
artificial intelligence
DFT optimization
molecular docking
Online Access:https://www.mdpi.com/1424-8247/16/1/49

Internet

https://www.mdpi.com/1424-8247/16/1/49

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