Soluble receptor for advanced glycation end products protects from ischemia- and reperfusion-induced acute kidney injury
The full-length receptor for advanced glycation end products (RAGE) is a multiligand pattern recognition receptor. High-mobility group box 1 (HMGB1) is a RAGE ligand of damage-associated molecular patterns that elicits inflammatory reactions. The shedded isoform of RAGE and endogenous secretory RAGE...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2022-01-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/11/1/bio058852 |