Soluble receptor for advanced glycation end products protects from ischemia- and reperfusion-induced acute kidney injury

The full-length receptor for advanced glycation end products (RAGE) is a multiligand pattern recognition receptor. High-mobility group box 1 (HMGB1) is a RAGE ligand of damage-associated molecular patterns that elicits inflammatory reactions. The shedded isoform of RAGE and endogenous secretory RAGE...

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Main Authors: Taro Miyagawa, Yasunori Iwata, Megumi Oshima, Hisayuki Ogura, Koichi Sato, Shiori Nakagawa, Yuta Yamamura, Yasutaka Kamikawa, Taito Miyake, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kengo Furuichi, Seiichi Munesue, Yasuhiko Yamamoto, Shuichi Kaneko, Takashi Wada
Format: Article
Language:English
Published: The Company of Biologists 2022-01-01
Series:Biology Open
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Online Access:http://bio.biologists.org/content/11/1/bio058852