A Novel Acetylation-Immune Subtyping for the Identification of a BET Inhibitor-Sensitive Subgroup in Melanoma

A Novel Acetylation-Immune Subtyping for the Identification of a BET Inhibitor-Sensitive Subgroup in Melanoma

Background: There have been significant advancements in melanoma therapies. BET inhibitors (BETis) show promise in impairing melanoma growth. However, identifying BETi-sensitive melanoma subtypes is challenging. Methods and Results: We analyzed 48 melanoma cell lines and 104 patients and identified...

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Bibliographic Details
Main Authors: Liuying Wang, Liuchao Zhang, Shuang Li, Lei Cao, Kang Li, Weiwei Zhao
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
histone acetylation
melanoma
acetylation-immune subtype
BET inhibitors
JQ-1
<i>KAT2A</i>
Online Access:https://www.mdpi.com/1424-8247/16/7/1037

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https://www.mdpi.com/1424-8247/16/7/1037

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