Impaired Neurovascular Function Underlies Poor Neurocognitive Outcomes and Is Associated with Nitric Oxide Bioavailability in Congenital Heart Disease

Impaired Neurovascular Function Underlies Poor Neurocognitive Outcomes and Is Associated with Nitric Oxide Bioavailability in Congenital Heart Disease

We use a non-invasive MRI proxy of neurovascular function (pnvf) to assess the ability of the vasculature to supply baseline metabolic demand, to compare pediatric and young adult congenital heart disease (CHD) patients to normal referents and relate the proxy to neurocognitive outcomes and nitric o...

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Bibliographic Details
Main Authors: Vanessa J. Schmithorst, Phillip S. Adams, Daryaneh Badaly, Vincent K. Lee, Julia Wallace, Nancy Beluk, Jodie K. Votava-Smith, Jacqueline G. Weinberg, Sue R. Beers, Jon Detterich, John C. Wood, Cecilia W. Lo, Ashok Panigrahy
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Metabolites
Subjects:
congenital heart disease
neuro-vascular function
neurocognition
nitric oxide bioavailability
Online Access:https://www.mdpi.com/2218-1989/12/9/882

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https://www.mdpi.com/2218-1989/12/9/882

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