A novel logical model of COVID-19 intracellular infection to support therapies development.

In this paper, a logical-based mathematical model of the cellular pathways involved in the COVID-19 infection has been developed to study various drug treatments (single or in combination), in different illness scenarios, providing insights into their mechanisms of action. Drug simulations suggest t...

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Bibliographic Details
Main Authors: Elena Piretto, Gianluca Selvaggio, Damiano Bragantini, Enrico Domenici, Luca Marchetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010443