Influence of Androgen Deprivation Therapy on the PD-L1 Expression and Immune Activity in Prostate Cancer Tissue

Influence of Androgen Deprivation Therapy on the PD-L1 Expression and Immune Activity in Prostate Cancer Tissue

Immune checkpoint inhibitors have become a promising new therapy for cancer treatment. However, due to prostate cancer’s high heterogeneity and immune-suppressive tumour microenvironment, clinical trials with immune checkpoint inhibitors for prostate cancer resulted in low or no response. This descr...

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Bibliographic Details
Main Authors: Ulrich Sommer, Celina Ebersbach, Alicia-Marie K. Beier, Gustavo B. Baretton, Christian Thomas, Angelika Borkowetz, Holger H. H. Erb
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
checkpoint inhibitors
immune therapy
PCA
ADT
tumour microenvironment (TME)
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.878353/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.878353/full

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