Regulatory T Cells in Colorectal Cancer: From Biology to Prognostic Relevance
Regulatory T cells (Tregs) were initially described as "suppressive" lymphocytes in the 1980s. However, it took almost 20 years until the concept of Treg-mediated immune control in its present form was finally established. Tregs are obligatory for self-tolerance and defects within their po...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-03-01
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| Series: | Cancers |
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| Online Access: | http://www.mdpi.com/2072-6694/3/2/1708/ |