Effect of sorafenib maintenance on Epstein-Barr virus and cytomegalovirus infections in patients with FLT3-ITD AML undergoing allogeneic hematopoietic stem cell transplantation: a secondary analysis of a randomized clinical trial

Effect of sorafenib maintenance on Epstein-Barr virus and cytomegalovirus infections in patients with FLT3-ITD AML undergoing allogeneic hematopoietic stem cell transplantation: a secondary analysis of a randomized clinical trial

Abstract Background Use of kinase inhibitors such as dasatinib and imatinib might increase the risk of opportunistic infections, especially Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infections. However, the effect of sorafenib on EBV and CMV infections remains unclear. The aim of this study...

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Main Authors: Xin Xu, Zhiping Fan, Yu Wang, Fen Huang, Yajing Xu, Jing Sun, Na Xu, Lan Deng, Xudong Li, Xinquan Liang, Xiaodan Luo, Pengcheng Shi, Hui Liu, Yan Chen, Sanfang Tu, Xiaojun Huang, Qifa Liu, Li Xuan
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Medicine
Subjects:
Sorafenib
Epstein-Barr virus
Cytomegalovirus
FLT3-ITD acute myeloid leukemia
Allogeneic hematopoietic stem cell transplantation
Online Access:https://doi.org/10.1186/s12916-022-02479-x

Internet

https://doi.org/10.1186/s12916-022-02479-x

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