Neuroprotective potential of quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

Neuroprotective potential of quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1-Methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that selectively damages dopaminergic neurons in the substantia nigra pars compacta and induces Parkinson's like symptoms in rodents. Quercetin (QC) is a natural polyphenolic bioflavonoid with potent antioxidant and anti-inflamm...

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Bibliographic Details
Main Authors: Shamsher Singh, Sumit Jamwal, Puneet Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; 1-methy-4-phenyl-1
2
3
6-tetrahydropyridine; Quercetin; Piperine; Parkinson′s disease; excitotoxicity; oxido-nitrosative stress; neurotransmitters; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=7;spage=1137;epage=1144;aulast=Singh

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=7;spage=1137;epage=1144;aulast=Singh

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