Subcellular localization of class I histone deacetylases in the developing Xenopus tectum

Subcellular localization of class I histone deacetylases in the developing Xenopus tectum

Histone deacetylases (HDACs) are thought to localize in the nucleus to regulate gene transcription and play pivotal roles in neurogenesis, apoptosis and plasticity. However, the subcellular distribution of class I HDACs in the developing brain remains unclear. Here, we show that HDAC1 and HDAC2 are...

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Bibliographic Details
Main Authors: Xia eGuo, Hangze eRuan, Xia eLi, Liming eQin, Yi eTao, Xianjie eQi, Juanmei eGao, Lin eGan, Shumin eDuan, Wanhua eShen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Histone Deacetylase 1
Histone Deacetylase Inhibitors
Histone Deacetylases
Mitochondria
Xenopus laevis
Subcellular localization
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00510/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00510/full

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