Development of elastin-like polypeptide for targeted specific gene delivery in vivo
Abstract Background The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient approaches for gene delivery but often compromised...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-020-0574-z |