The Molecular Pathogenesis of Tumor-Suppressive <i>miR-486-5p</i> and <i>miR-486-3p</i> Target Genes: <i>GINS4</i> Facilitates Aggressiveness in Lung Adenocarcinoma

The Molecular Pathogenesis of Tumor-Suppressive <i>miR-486-5p</i> and <i>miR-486-3p</i> Target Genes: <i>GINS4</i> Facilitates Aggressiveness in Lung Adenocarcinoma

The involvement of passenger strands of miRNAs in the molecular pathogenesis of human cancers is a recent concept in miRNA research, and it will broaden our understanding of the molecular mechanisms of miRNA-mediated cancer. The analysis of our miRNA signature of LUAD revealed that both strands of p...

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Bibliographic Details
Main Authors: Yuya Tomioka, Takayuki Suetsugu, Naohiko Seki, Kengo Tanigawa, Yoko Hagihara, Masahiro Shinmura, Shunichi Asai, Naoko Kikkawa, Hiromasa Inoue, Keiko Mizuno
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
microRNA
passenger strand
<i>miR-486-5p</i>
<i>miR-486-3p</i>
<i>GINS4</i>
lung adenocarcinoma
Online Access:https://www.mdpi.com/2073-4409/12/14/1885

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https://www.mdpi.com/2073-4409/12/14/1885

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