<i>Mycobacterium bovis</i> Wild-Type BCG or Recombinant BCG Secreting Murine IL-18 (rBCG/IL-18) Strains in Driving Immune Responses in Immunocompetent or Immunosuppressed Mice

<i>Mycobacterium bovis</i> Wild-Type BCG or Recombinant BCG Secreting Murine IL-18 (rBCG/IL-18) Strains in Driving Immune Responses in Immunocompetent or Immunosuppressed Mice

<i>Mycobacterium tuberculosis</i> infections remain a global health problem in immunosuppressed patients. The effectiveness of BCG (Bacillus Calmette–Guérin), an anti-tuberculosis vaccine, is unsatisfactory. Finding a new vaccine candidate is a priority. We compared numerous immune marke...

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Bibliographic Details
Main Authors: Marek Fol, Marcin Włodarczyk, Magdalena Kowalewicz-Kulbat, Magdalena Druszczyńska, Krzysztof T. Krawczyk, Sebastian Wawrocki, Wiesława Rudnicka, Magdalena Chmiela
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Vaccines
Subjects:
BCG
IL-18
immunosuppression
cyclophosphamide
immunity
C3H
Online Access:https://www.mdpi.com/2076-393X/10/4/615

Internet

https://www.mdpi.com/2076-393X/10/4/615

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