CORM-2-entrapped ultradeformable liposomes ameliorate acute skin inflammation in an ear edema model via effective CO delivery

CORM-2-entrapped ultradeformable liposomes ameliorate acute skin inflammation in an ear edema model via effective CO delivery

The short release half-life of carbon monoxide (CO) is a major obstacle to the effective therapeutic use of carbon monoxide-releasing molecule-2 (CORM-2). The potential of CORM-2-entrapped ultradeformable liposomes (CORM-2-UDLs) to enhance the release half-life of CO and alleviate skin inflammation...

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Bibliographic Details
Main Authors: Gwan-Yeong Lee, Alam Zeb, Eun-Hye Kim, Beomseon Suh, Young-Jun Shin, Donghyun Kim, Kyoung-Won Kim, Yeong-Hwan Choe, Ho-Ik Choi, Cheol-Ho Lee, Omer Salman Qureshi, In-Bo Han, Sun-Young Chang, Ok-Nam Bae, Jin-Ki Kim
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Carbon monoxide
CORM-2
Anti-inflammatory effect
Ultradeformable liposomes
Skin inflammation
Ear edema
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383520305931

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http://www.sciencedirect.com/science/article/pii/S2211383520305931

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