Congenital insensitivity to pain associated with PRDM12 mutation: Two case reports and a literature review

Congenital insensitivity to pain associated with PRDM12 mutation: Two case reports and a literature review

Background:PRDM12 is a newly discovered gene responsible for congenital insensitivity to pain (CIP). Its clinical manifestations are various and not widely known.Methods: The clinical data of two infants diagnosed with CIP associated with PRDM12 mutation were collected. A literature review was perfo...

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Bibliographic Details
Main Authors: Hanrui Yu, Jie Wu, Jinju Cong, Mingxiong Chen, Yifei Huang, Jifeng Yu, Liqiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Genetics
Subjects:
Prdm12
insensitivity to pain
corneal disease
self-mutilation behavior
HSAN
hereditary and sensory autonomic neuropathy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1139161/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1139161/full

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