A Role for H<sub>2</sub>O<sub>2</sub> and TRPM2 in the Induction of Cell Death: Studies in KGN Cells

A Role for H<sub>2</sub>O<sub>2</sub> and TRPM2 in the Induction of Cell Death: Studies in KGN Cells

Recent studies showed that KGN cells, derived from a human granulosa cell tumor (GCT), express NADPH oxidase 4 (NOX4), an important source of H<sub>2</sub>O<sub>2</sub>. Transient receptor potential melastatin 2 (TRPM2) channel is a Ca<sup>2+</sup> permeable catio...

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Bibliographic Details
Main Authors: Carsten Theo Hack, Theresa Buck, Konstantin Bagnjuk, Katja Eubler, Lars Kunz, Doris Mayr, Artur Mayerhofer
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Antioxidants
Subjects:
ovary
calcium channel
trolox
granulosa cell tumor
cell death
mitochondria
Online Access:https://www.mdpi.com/2076-3921/8/11/518

Internet

https://www.mdpi.com/2076-3921/8/11/518

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