Locked Out: Phoenixin-14 Does Not Cross a Stem-Cell-Derived Blood–Brain Barrier Model

Phoenixin-14 is a recently discovered peptide regulating appetite. Interestingly, it is expressed in the gastrointestinal tract; however, its supposed receptor, GPR173, is predominantly found in hypothalamic areas. To date, it is unknown how peripherally secreted phoenixin-14 is able to reach its ce...

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Bibliographic Details
Main Authors: Martha A. Schalla, Sabrina Oerter, Alevtina Cubukova, Marco Metzger, Antje Appelt-Menzel, Andreas Stengel
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/13/7/980