In vitro and in silico study on the effect of carvedilol and sorafenib alone and in combination on the growth and inflammatory response of melanoma cells

In vitro and in silico study on the effect of carvedilol and sorafenib alone and in combination on the growth and inflammatory response of melanoma cells

Melanoma is an aggressive skin cancer. Increasing evidence has shown the role of β-adrenergic receptors in the pathogenesis of melanoma. Carvedilol is a widely used non-selective β-AR antagonist with potential anticancer activity. The purpose of the study was to estimate the influence of carvedilol...

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Bibliographic Details
Main Authors: Joanna Wawszczyk, Radosław Wolan, Sławomir Smolik, Małgorzata Kapral
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Saudi Pharmaceutical Journal
Subjects:
Sorafenib
Carvedilol
Melanoma
β-blocker
Combination treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423001391

Internet

http://www.sciencedirect.com/science/article/pii/S1319016423001391

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