Tentatively Identified (UPLC/T-TOF–MS/MS) Compounds in the Extract of <i>Saussurea costus</i> Roots Exhibit In Vivo Hepatoprotection via Modulation of HNF-1α, Sirtuin-1, C/ebpα, miRNA-34a and miRNA-223

Tentatively Identified (UPLC/T-TOF–MS/MS) Compounds in the Extract of <i>Saussurea costus</i> Roots Exhibit In Vivo Hepatoprotection via Modulation of HNF-1α, Sirtuin-1, C/ebpα, miRNA-34a and miRNA-223

<i>Saussurea costus</i> is a plant traditionally used for the treatment of several ailments. Our study accomplished the UPLC/T-TOF–MS/MS analysis of a methanol extract of <i>Saussurea costus</i> roots (MESC), in addition to lipoidal matter determination and assessment of its...

Full description

Bibliographic Details
Main Authors: Heba A. El Gizawy, Alaadin E. El-Haddad, Amr M. Saadeldeen, Sylvia A. Boshra
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
<i>Saussurea lappa</i>
Asteraceae
phenolics
hepatoprotective
HNF-1α
C/ebpα
Online Access:https://www.mdpi.com/1420-3049/27/9/2802

Internet

https://www.mdpi.com/1420-3049/27/9/2802

Similar Items