Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair.

Centrosomes, the principal microtubule-organising centres in animal cells, contain centrins, small, conserved calcium-binding proteins unique to eukaryotes. Centrin2 binds to xeroderma pigmentosum group C protein (XPC), stabilising it, and its presence slightly increases nucleotide excision repair (...

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Bibliographic Details
Main Authors: Tiago J Dantas, Owen M Daly, Pauline C Conroy, Martin Tomas, Yifan Wang, Pierce Lalor, Peter Dockery, Elisa Ferrando-May, Ciaran G Morrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699651?pdf=render