Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease.

Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease.

A seeming paradox of sickle cell disease is that patients do not suffer from a high prevalence of systemic hypertension in spite of endothelial dysfunction, chronic inflammation and vasculopathy. However, some patients do develop systolic hypertension and increased pulse pressure, an increasingly re...

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Bibliographic Details
Main Authors: Enrico M Novelli, Mariana Hildesheim, Caterina Rosano, Rebecca Vanderpool, Marc Simon, Gregory J Kato, Mark T Gladwin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4257593?pdf=render

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http://europepmc.org/articles/PMC4257593?pdf=render

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