Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model

Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model

Abstract Background Porcine circovirus type 2 (PCV2) is one of the major pathogens commonly found in pigs, which causes immunosuppression and apoptosis. Vaccination and a single drug cannot totally prevent and treat PCV2 infection. Our previous in vitro study reported that the synergistic anti-PCV2...

Full description

Bibliographic Details
Main Authors: Yinlan Xu, Shuangxiu Wan, Panpan Sun, Ajab Khan, Jianhua Guo, Xiaozhong Zheng, Yaogui Sun, Kuohai Fan, Wei Yin, Hongquan Li, Na Sun
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Veterinary Research
Subjects:
Matrine
Osthole
PCV2
GRP78
Apoptosis
PERK
Online Access:https://doi.org/10.1186/s12917-023-03581-9

Internet

https://doi.org/10.1186/s12917-023-03581-9

Similar Items