Small interfering RNA targeting of keratin 17 reduces inflammation in imiquimod-induced psoriasis-like dermatitis

Abstract. Background. Psoriasis is a common chronic inflammatory skin disease with 2% to 3% prevalence worldwide and a heavy social-psychological burden for patients and their families. As the exact pathogenesis of psoriasis is still unknown, the current treatment is far from satisfactory. Thus, the...

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Bibliographic Details
Main Authors: Chun-Ying Xiao, Zhen-Lai Zhu, Chen Zhang, Meng Fu, Hong-Jiang Qiao, Gang Wang, Er-Le Dang, Xin Chen, Yuan-Yuan Ji
Format: Article
Language:English
Published: Wolters Kluwer 2020-12-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001197