Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

<p>Abstract</p> <p>Background</p> <p>Down syndrome (DS), caused by trisomy of human chromosome 21 (HSA21), is the most common genetic birth defect. Congenital heart defects (CHD) are seen in 40% of DS children, and >50% of all atrioventricular canal defects in infanc...

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Bibliographic Details
Main Authors: Cotter Finbarr E, Groet Jürgen, Veltman Joris, Hoischen Alex, Burt Emma, Delom Frédéric, Nizetic Dean
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Proteome Science
Online Access:http://www.proteomesci.com/content/7/1/31

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http://www.proteomesci.com/content/7/1/31

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