Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells.

Ceruloplasmin, the main copper binding protein in blood plasma, has been of particular interest for its role in efflux of iron from cells, but has additional functions. Here we tested the hypothesis that it releases its copper for cell uptake by interacting with a cell surface reductase and transpor...

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Bibliographic Details
Main Authors: Danny Ramos, David Mar, Michael Ishida, Rebecca Vargas, Michaella Gaite, Aaron Montgomery, Maria C Linder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4774968?pdf=render