Strain Prioritization and Genome Mining for Enediyne Natural Products
ABSTRACT The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date. Here we report a genome survey of 3,400 actinomycetes, identifying 81 strains that harbor genes encoding the...
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-12-01
|
Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.02104-16 |