Fibroblast exosomal TFAP2C induced by chitosan oligosaccharides promotes peripheral axon regeneration via the miR-132-5p/CAMKK1 axis

Fibroblast exosomal TFAP2C induced by chitosan oligosaccharides promotes peripheral axon regeneration via the miR-132-5p/CAMKK1 axis

Chitosan and its degradation product, oligosaccharides, have been shown to facilitate peripheral nerve regeneration. However, the underlying mechanisms are not well understood. In this study, we analyzed the protein expression profiles in sciatic nerves after injury using proteomics. A group of prot...

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Bibliographic Details
Main Authors: Yahong Zhao, Jina Liu, Sha Liu, Panpan Yang, Yunyun Liang, Jinyu Ma, Susu Mao, Cheng Sun, Yumin Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-08-01
Series:Bioactive Materials
Subjects:
peripheral nerves
chitosan oligosaccharides
fibroblast exosomes
TFAP2C
axon regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23000798

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http://www.sciencedirect.com/science/article/pii/S2452199X23000798

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