Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice

Introduction: The angiotensin converting enzyme inhibitor ramipril is a standard antihypertensive therapy for many patients. Because angiotensin II may promote inflammation, we were interested in whether basal pretreatment with ramipril may modify renal function and inflammation as well as systemic...

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Bibliographic Details
Main Authors: Tzvetanka Bondeva, Katrin Schindler, Claudia Schindler, Gunter Wolf
Format: Article
Language:English
Published: SAGE Publications 2020-05-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320320923977