Altered Glycosylation of Human Alpha-1-Acid Glycoprotein as a Biomarker for Malignant Melanoma

Altered Glycosylation of Human Alpha-1-Acid Glycoprotein as a Biomarker for Malignant Melanoma

A high-resolution HILIC-MS/MS method was developed to analyze anthranilic acid derivatives of <i>N</i>-glycans released from human serum alpha-1-acid glycoprotein (AGP). The method was applied to samples obtained from 18 patients suffering from high-risk malignant melanoma as well as 19...

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Bibliographic Details
Main Authors: Dávid Virág, Tibor Kremmer, Kende Lőrincz, Norbert Kiss, Antal Jobbágy, Szabolcs Bozsányi, Lili Gulyás, Norbert Wikonkál, Gitta Schlosser, Adina Borbély, Zsófia Huba, Borbála Dalmadi Kiss, István Antal, Krisztina Ludányi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
alpha-1-acid glycoprotein
biomarker
glycosylation
hydrophilic interaction chromatography
linear discriminant analysis
mass spectrometry
Online Access:https://www.mdpi.com/1420-3049/26/19/6003

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https://www.mdpi.com/1420-3049/26/19/6003

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