Lectin-like oxidized LDL receptor-1 is an enhancer of tumor angiogenesis in human prostate cancer cells.

Altered expression and function of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) has been associated with several diseases such as endothelial dysfunction, atherosclerosis and obesity. In these pathologies, oxLDL/LOX-1 activates signaling pathways that promote cell proliferation, c...

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Main Authors: Iván González-Chavarría, Rita P Cerro, Natalie P Parra, Felipe A Sandoval, Felipe A Zuñiga, Valeska A Omazábal, Liliana I Lamperti, Silvana P Jiménez, Edelmira A Fernandez, Nicolas A Gutiérrez, Federico S Rodriguez, Sergio A Onate, Oliberto Sánchez, Juan C Vera, Jorge R Toledo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149537?pdf=render