Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles
Existing optogenetic silencing methods affect membrane potential, biochemistry or protein integrity. Here, the authors demonstrate an approach for silencing synaptic transmission that combines fast activation and reversibility, by using nondisruptive, reversible, light-evoked clustering of synaptic...
Auteurs principaux: | , , , , , , , , , |
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Format: | Article |
Langue: | English |
Publié: |
Nature Portfolio
2022-12-01
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Collection: | Nature Communications |
Accès en ligne: | https://doi.org/10.1038/s41467-022-35324-z |