Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles

Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles

Existing optogenetic silencing methods affect membrane potential, biochemistry or protein integrity. Here, the authors demonstrate an approach for silencing synaptic transmission that combines fast activation and reversibility, by using nondisruptive, reversible, light-evoked clustering of synaptic...

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Bibliographic Details
Main Authors: Dennis Vettkötter, Martin Schneider, Brady D. Goulden, Holger Dill, Jana Liewald, Sandra Zeiler, Julia Guldan, Yilmaz Arda Ateş, Shigeki Watanabe, Alexander Gottschalk
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35324-z

Internet

https://doi.org/10.1038/s41467-022-35324-z

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