Activity of praziquantel on in vitro transformed Schistosoma mansoni sporocysts

Praziquantel (PZQ) is effective against all the evolutive phases of Schistosoma mansoni. Infected Biomphalaria glabrata snails have their cercarial shedding interrupted when exposed to PZQ. Using primary in vitro transformed sporocysts, labeled with the probe Hoechst 33258 (indicator of membrane int...

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Bibliographic Details
Main Authors: ACA Mattos, JR Kusel, PFP Pimenta, PMZ Coelho
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2006-10-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000900044