SMAD4 promotes somatic-germline contact during murine oocyte growth

Development of the mammalian oocyte requires physical contact with the surrounding granulosa cells of the follicle, which provide it with essential nutrients and regulatory signals. This contact is achieved through specialized filopodia, termed transzonal projections (TZPs), that extend from the gra...

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Bibliographic Details
Main Authors: Sofia Granados-Aparici, Qin Yang, Hugh J Clarke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/91798