Low expression of CD39 and CD73 genes in centenarians compared with octogenarians

Low expression of CD39 and CD73 genes in centenarians compared with octogenarians

Abstract Ageing involves a progressive decline of the body’s regulatory systems including immune system. Adenosine regulates immune function by interaction with its receptors, mainly adenosine A2A receptor, present on the surface of immune cells. Furthermore, cellular response to this nucleoside is...

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Bibliographic Details
Main Authors: Almudena Crooke, Juan Martínez-Henández, Joaquín Martínez-López, Alfonso Cruz-Jentoft, Fernando Huete-Toral, Jesús Pintor
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Immunity & Ageing
Subjects:
Ageing
Centenarian
Adenosine receptor
Ecto-nucleotidase
Online Access:http://link.springer.com/article/10.1186/s12979-017-0094-3

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http://link.springer.com/article/10.1186/s12979-017-0094-3

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