Low expression of CD39 and CD73 genes in centenarians compared with octogenarians
Abstract Ageing involves a progressive decline of the body’s regulatory systems including immune system. Adenosine regulates immune function by interaction with its receptors, mainly adenosine A2A receptor, present on the surface of immune cells. Furthermore, cellular response to this nucleoside is...
Main Authors: | Almudena Crooke, Juan Martínez-Henández, Joaquín Martínez-López, Alfonso Cruz-Jentoft, Fernando Huete-Toral, Jesús Pintor |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12979-017-0094-3 |
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