Memantine increases the dendritic complexity of hippocampal young neurons in the juvenile brain after cranial irradiation

Memantine increases the dendritic complexity of hippocampal young neurons in the juvenile brain after cranial irradiation

IntroductionCranial irradiation (IR) negatively regulates hippocampal neurogenesis and causes cognitive dysfunctions in cancer survivors, especially in pediatric patients. IR decreases proliferation of neural stem/progenitor cells (NSPC) and consequently diminishes production of new hippocampal neur...

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Detalles Bibliográficos
Main Authors: Georgios Alkis Zisiadis, Androniki Alevyzaki, Elene Nicola, Carlos F. D. Rodrigues, Klas Blomgren, Ahmed M. Osman
Formato: Artigo
Idioma:English
Publicado: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
radiotherapy
neurogenesis
neural stem cells
doublecortin
NMDA antagonist
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2023.1202200/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1202200/full

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