Memantine increases the dendritic complexity of hippocampal young neurons in the juvenile brain after cranial irradiation
IntroductionCranial irradiation (IR) negatively regulates hippocampal neurogenesis and causes cognitive dysfunctions in cancer survivors, especially in pediatric patients. IR decreases proliferation of neural stem/progenitor cells (NSPC) and consequently diminishes production of new hippocampal neur...
Main Authors: | Georgios Alkis Zisiadis, Androniki Alevyzaki, Elene Nicola, Carlos F. D. Rodrigues, Klas Blomgren, Ahmed M. Osman |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-10-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1202200/full |
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