KI-Mediated Three-component Reaction of Hydroxylamine Hydrochloride with Aryl/Heteroaryl Aldehydes and Two β-Oxoesters

A KI-mediated multi-component cyclocondensation of hydroxylamine hydrochloride, aromatic/hetero-aromatic aldehydes, and   ethyl acetoacetate or 4-chloroethyl acetoacetate to form isoxazole-5(4H)-one heterocycles is described. The reaction employs readily accessible starting reactants and provides a...

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Bibliographic Details
Main Authors: Asiyeh Mosallanezhad, Hamzeh Kiyani
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2018-04-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
Online Access:https://periodicos.ufms.br/index.php/orbital/article/view/16366