Effect of molecular weight and tissue layer on solute partitioning in the knee meniscus

Objective: Knee meniscus tissue is partly vascularized, meaning that nutrients must be transported through the extracellular matrix of the avascular portion to reach resident cells. Similarly, drugs used as therapeutic agents to treat meniscal pathologies rely on transport through the tissue. The dr...

Full description

Bibliographic Details
Main Authors: Andy Morejon, Gabi Schwartz, Thomas M. Best, Francesco Travascio, Alicia R. Jackson
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913123000274